首页 > 新闻公告 > CEM研究国际动态 CEM研究国际动态
Palladium-catalysed synthesis of triaryl(heteroaryl)methanes

Tetraarylmethane derivatives are desirable for a variety of applications, but difficult to access with modern C–C bond-forming reactions. Here we report a straightforward method for palladium-catalysed arylation of aryl(heteroaryl)methanes and diaryl(heteroaryl)methanes with aryl chlorides. This reaction enables introduction of various aryl groups to construct triaryl(heteroaryl)methanes via a C–H functionalization in good to excellent yield, and represents the first step towards a general transition metal catalysed synthesis of tetraarylmethanes.

Nature Communications 8, Article number: 14641 (2017)
doi:10.1038/ncomms14641

http://www.nature.com/articles/ncomms14641

发布日期:2017/03/17 发布者:网站管理员 点击数: